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Article

KSHV Reprogramming of Host Energy Metabolism for Pathogenesis

12 May 2021

Abstract excerpt

Reprogramming of energy metabolism is a key for cancer development. Kaposi's sarcoma-associated herpesvirus (KSHV), a human oncogenic herpesvirus, is tightly associated with several human malignancies by infecting B-lymphocyte or endothelial cells. Cancer cell energy metabolism is mainly dominated by three pathways of central carbon metabolism, including aerobic glycolysis, glutaminolysis, and fatty acid...

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PMID: 34055662
DOI: 10.3389/fcimb.2021.621156

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