Article
Human Cytomegalovirus: Coordinating Cellular Stress, Signaling, and Metabolic Pathways
1 Oct 2014
Abstract excerpt
Viruses face a multitude of challenges when they infect a host cell. Cells have evolved innate defenses to protect against pathogens, and an infecting virus may induce a stress response that antagonizes viral replication. Further, the metabolic, oxidative, and cell cycle state may not be conducive to the viral infection. But viruses are fabulous manipulators, inducing host cells to use their own characteristic...
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