Article

Pan-cancer evaluation of clinical value of mitotic network activity index (MNAI) and its predictive value of immunotherapy

2023-01-24

Abstract excerpt

Increased mitotic activity is associated with the genesis and aggressiveness of many cancers. To assess the clinical value of mitotic activity as prognostic biomarker, we performed a pan-cancer study on the mitotic network activity index (MNAI) constructed based on 54-gene mitotic apparatus network. Our pan-cancer assessment on TCGA (33 tumor types, 10,061 patients) and validation on other publicly available cohor...

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Literature Corpus work: 3005af52-5197-520e-90ea-f5a7b80c9d91
DOI: 10.20944/preprints202301.0434.v1

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