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Controlling astrocyte-mediated synaptic pruning signals for schizophrenia drug repurposing with Deep Graph Networks

2021-10-09

Abstract excerpt

Schizophrenia is a debilitating psychiatric disorder, leading to both physical and social morbidity. Worldwide 1% of the population is struggling with the disease, with 100,000 new cases annually only in the United States. Despite its importance, the goal of finding effective treatments for schizophrenia remains a challenging task, and previous work conducted expensive large-scale phenotypic screens. This work inv...

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Literature Corpus work
2fa33240-bc70-5e81-999a-a707364b8e56
DOI
10.1101/2021.10.07.463459
Open publication

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Controlling astrocyte-mediated synaptic pruning signals for schizophrenia drug repurposing with Deep Graph NetworksDOI 10.1101/2021.10.07.463459
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