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A vimentin-targeting oral compound with host-directed antiviral and anti-inflammatory actions addresses multiple features of COVID-19 and related diseases

2021-08-27

Abstract excerpt

<h4>ABSTRACT</h4> Damage in COVID-19 results from both the SARS-CoV-2 virus and its triggered overreactive host immune responses. Therapeutic agents that focus solely on reducing viral load or hyperinflammation fail to provide satisfying outcomes in all cases. Although viral and cellular factors have been extensively profiled to identify potential anti-COVID targets, new drugs with significant efficacy remain to...

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Literature Corpus work
2f9c33db-1eda-5801-897d-f19a38bbd137
DOI
10.1101/2021.08.26.457884
Open publication

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A vimentin-targeting oral compound with host-directed antiviral and anti-inflammatory actions addresses multiple features of COVID-19 and related diseasesDOI 10.1101/2021.08.26.457884
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