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D-mannose suppresses macrophage release of extracellular vesicles and ameliorates type 2 diabetes

2024-02-19

Abstract excerpt

The monosaccharide D-mannose exists naturally in low abundance in human blood, while an increased plasma mannose level is associated with insulin resistance and the incidence of type 2 diabetes (T2D) in patients. However, whether and how D-mannose may regulate T2D development remains elusive. Here, we show that despite the altered mannose metabolism in T2D, drinking-water supplementation of supraphysiological D-ma...

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Literature Corpus work
2f74292d-1bd0-5d31-9dc0-cafdf14a585a
DOI
10.1101/2024.02.18.580856
Open publication

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D-mannose suppresses macrophage release of extracellular vesicles and ameliorates type 2 diabetesDOI 10.1101/2024.02.18.580856
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