Article
Cross-tissue multiomics reveals that Akkermansia muciniphila counteracts metabolic syndrome by reprograming gut microbiota, oleoylethanolamide and the gut-hypothalamus axis
2022-09-08
Abstract excerpt
High fructose diet is a major risk factor for metabolic syndrome (MetS). The gut bacterium Akkermansia muciniphila (A. muciniphila) has been shown to improve fructose-induced MetS, but the underlying mechanism remains unclear. Here, we investigated how A. muciniphila modulates fructose-induced MetS using multitissue, multiomics studies encompassing gut microbiota, plasma and gut metabolome, and hypothalamus single...
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Identifiers and source
- Literature Corpus work
- 5cc0e5a3-0342-5c05-aafc-b8cb6f7d0d2a
- DOI
- 10.1101/2022.09.06.506855
