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Comprehensive Network of Signaling Pathways in Hepatocellular Carcinoma and Network Analysis Reveals PTK2, GSK3β, and β-catenin to be Crucial for Cancer Progression

2025-07-30

Abstract excerpt

Hepatocellular carcinoma (HCC) is a highly aggressive primary liver cancer with significant morbidity and mortality. The development and progression of HCC involves several genetic mutations, alterations in signaling pathways leading to dysregulation of cellular processes. Several investigations have demonstrated the involvement of diverse regulators and their complex signaling cascades in progression of HCC. Unde...

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Literature Corpus work
2f72000b-096e-5a65-a207-31f4e0c58d50
DOI
10.1101/2025.07.25.666714
Open publication

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Comprehensive Network of Signaling Pathways in Hepatocellular Carcinoma and Network Analysis Reveals PTK2, GSK3β, and β-catenin to be Crucial for Cancer ProgressionDOI 10.1101/2025.07.25.666714
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