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Network-based analysis of candidate oncogenes and pathways in hepatocellular carcinoma

10 Jun 2025

Abstract excerpt

Hepatocellular carcinoma (HCC) is a major worldwide health burden due to poor outcomes. Identifying dysregulated molecular circuits in HCC is critical for developing precise treatments. A systems-level approach using multi-omics data is required to reveal the intricate non-linear interactions underlying liver carcinogenesis. Both tumor and control tissues contained differentially expressed genes (DEGs). Hub genes...

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PMID: 40546347
DOI: 10.1016/j.bbrep.2025.102086

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