Article

Predicting mesenchymal stem cells potential for cardiac repair by clinical indicators and inducing differentiation to cardiomyocytes in vitro by mimicry of in vivo microenvironment

2025-10-15

Abstract excerpt

<title>Abstract</title> <p>Patient-specific factors critically influence the therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) for cardiac regeneration. In this work, we identify lymphocyte count as a key clinical predictor of BM-MSC proliferative capacity, with coronary artery disease significantly delaying expansion in patients undergoing cardiac surgery. Thus, we established cell se...

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Literature Corpus work: 2f4eb0ad-1cce-531d-b9c8-c0746d747fe7
DOI: 10.21203/rs.3.rs-7047558/v1

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Predicting mesenchymal stem cells potential for cardiac repair by clinical indicators and inducing differentiation to cardiomyocytes in vitro by mimicry of in vivo microenvironmentDOI 10.21203/rs.3.rs-7047558/v1Read

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