Article
The influence of cardiovascular risk factors on bone marrow mesenchymal stromal cell fitness.
Cytotherapy - 1 Jul 2012
Neef Klaus, Choi Yeong-Hoon, Weichel Angelika, Rahmanian Parwis Baradaran, Liakopoulos Oliver Joannis, Stamm Christof, Choi Claudia Yeong-Un, Jacobshagen Claudius, Wittwer Thorsten, Wahlers Thorsten
Abstract excerpt
BACKGROUND AIMS: In the past, cell transplantation strategies for the treatment of heart failure have shown promising results in experimental and clinical studies. Bone marrow (BM)-derived stem cells represent the most frequently used cell population. Within this heterogeneous cell population, mesenchymal stromal cells (MSC) have been identified to induce therapeutic effects, mainly through paracrine mechanisms....
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