Article

Mini-Review: Convergent Evolutionary Mechanisms of Pulmonary Adaptation to Hypoxia and Fibrosis in High-Altitude and Marine Mammals

2025-07-11

Abstract excerpt

High-altitude and marine mammals inhabit vastly different ecosystems yet share the selective pressure of chronic hypoxia. Convergent evolutionary adaptations, particularly in pulmonary architecture with increased elastic fibers, facilitate efficient oxygen use under hypoxia. This review synthesizes molecular insights into these adaptations, highlighting gene family dynamics, positive selection, and convergent amin...

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Literature Corpus work: 2ee737a3-e750-5735-9421-b3684a662956
DOI: 10.20944/preprints202507.1017.v1

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