Article
<i>Enterococcal</i> PrgU mitigates PrgB overexpression toxicity by binding to intergenic RNA downstream of the P <sub>Q</sub> promoter
2020-07-07
Abstract excerpt
Efficient horizontal gene transfer of the conjugative plasmid pCF10 from Enterococcus faecalis depends on the sex pheromone cCF10, which induces the expression of the Type 4 Secretion System (T4SS) genes controlled by the P Q promoter. The pheromone responsive P Q promoter is strictly regulated to prevent overproduction of the prgQ operon, which contains the T4SS, and to limit the cell toxicity caused by overp...
Identifiers and source
- Literature Corpus work
- 2eda994b-fdc2-593b-8bfd-42f2d548044e
- DOI
- 10.1101/2020.07.06.190884
