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<i>Enterococcal</i> PrgU mitigates PrgB overexpression toxicity by binding to intergenic RNA downstream of the P <sub>Q</sub> promoter

2020-07-07

Abstract excerpt

Efficient horizontal gene transfer of the conjugative plasmid pCF10 from Enterococcus faecalis depends on the sex pheromone cCF10, which induces the expression of the Type 4 Secretion System (T4SS) genes controlled by the P Q promoter. The pheromone responsive P Q promoter is strictly regulated to prevent overproduction of the prgQ operon, which contains the T4SS, and to limit the cell toxicity caused by overp...

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Literature Corpus work
2eda994b-fdc2-593b-8bfd-42f2d548044e
DOI
10.1101/2020.07.06.190884
Open publication

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<i>Enterococcal</i> PrgU mitigates PrgB overexpression toxicity by binding to intergenic RNA downstream of the P <sub>Q</sub> promoterDOI 10.1101/2020.07.06.190884
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