Article
Analysis of the amino acid sequence specificity determinants of the enterococcal cCF10 sex pheromone in interactions with the pheromone-sensing machinery.
Journal of bacteriology - 1 Feb 2007
Fixen Kathryn R, Chandler Josephine R, Le Thinh, Kozlowicz Briana K, Manias Dawn A, Dunny Gary M
Abstract excerpt
The level of expression of conjugation genes in Enterococcus faecalis strains carrying the pheromone-responsive transferable plasmid pCF10 is determined by the ratio in the culture medium of two types of signaling peptides, a pheromone (cCF10) and an inhibitor (iCF10). Recent data have demonstrated that both peptides target the cytoplasmic receptor protein PrgX. However, the relative importance of the interaction...
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