Article
Two targets in pCF10 DNA for PrgX binding: their role in production of Qa and prgX mRNA and in regulation of pheromone-inducible conjugation.
Journal of molecular biology - 1 Feb 2002
Bae Taeok, Kozlowicz Briana, Dunny Gary M
Abstract excerpt
PrgX is the primary cytoplasmic protein involved in negative control of pheromone-inducible conjugation functions of the Enterococcus faecalis plasmid pCF10. PrgX is believed to act in concert with an antisense RNA called Qa to inhibit readthrough of transcription from the prgQ promoter into the pCF10 genes mediating conjugation functions; PrgX also positively regulates its own expression, as well as that of Qa....
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