Article

Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages

2018-09-25

Abstract excerpt

Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic/blood-stream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood. Here, we report that Salmonella infection generates directional electric fields (EF) in the follicle-associated epithelium of mouse cecum. In vitro application of an EF, mimicking the infection...

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Literature Corpus work: 2ecbae70-c993-53b6-8445-9b9eb9965551
DOI: 10.1101/427294

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