Article

Alpha-Lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels

2022-11-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Neurodegeneration with brain iron accumulation (NBIA) disorders are a group of neurodegenerative diseases that have in common the accumulation of iron in the basal nuclei of the brain which are essential components of the extrapyramidal system. Frequent symptoms are progressive spasticity, dystonia, muscle rigidity, neuropsychiatric symptoms, and retinal degenera...

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Literature Corpus work: 2eb55bd7-bc0a-5729-8588-207db68d42e0
DOI: 10.21203/rs.3.rs-2268421/v1

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