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Down Regulation Of The Expression Of Mitochondrial Phosphopantetheinyl-Proteins In Pantothenate Kinase-Associated Neurodegeneration: Pathophysiological Consequences and Therapeutic Perspectives

2021-01-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Neurodegeneration with brain iron accumulation (NBIA) is a group of genetic neurological disorders frequently associated with iron accumulation in the basal nuclei of the brain characterized by progressive spasticity, dystonia, muscle rigidity, neuropsychiatric symptoms, and retinal degeneration or optic nerve atrophy. Pantothenate kinase-associated neurodegenerat...

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Literature Corpus work: 55d2de00-3d5a-5e15-968a-c816b22654cb
DOI: 10.21203/rs.3.rs-139018/v1

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