Article

Toddalolactone Protects Against Osteoarthritis by Ameliorating Chondrocyte Inflammation and Suppressing Osteoclastogenesis

2021-12-28

Abstract excerpt

<h4>Background: </h4> Osteoarthritis (OA) is widely recognized as the most common chronic joint disease accompanied by progressive cartilage and subchondral bone damage. Toddalolactone (TOD), a natural compound extracted from Toddalia asiatica (L.) Lam., has been widely used in the treatment of stroke, rheumatoid arthritis, and oedema. Nevertheless, what TOD acts as in the pathogenesis and progression of OA hasn’t...

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Literature Corpus work: 2eb4fe20-f46b-518b-ba7f-480d918c6629
DOI: 10.21203/rs.3.rs-1170145/v1

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