Article
Epigenetics and Herbs: Potential Therapeutic Strategies for Osteoarthritis of the Knee
1 Jun 2025
Abstract excerpt
Knee osteoarthritis (KOA) is a complex joint disease characterized by progressive cartilage degeneration with programmed cell death of chondrocytes. Programmed cell death (PCD) of chondrocytes plays a central role in the development of knee osteoarthritis, and epigenetics provides new explanations for this complex biological process. By regulating DNA methylation, histone modification and non-coding RNA,...
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