Article

Genomic Signatures and Functional Pathways Underlying 5-Fluorouracil Resistance in Head and Neck Cancer associated Streptococci

2026-02-25

Abstract excerpt

<title>Abstract</title> The chemotherapeutic agent 5-fluorouracil (5-FU), widely used in the treatment of head and neck cancer (HNC), also exhibits broad antimicrobial activity, yet fluoropyrimidine resistance within HNC-associated microbiota remains poorly characterised. We assessed 5-FU susceptibility and resistance-associated genomic features in 101 <italic>Streptococcus</italic> isolates obtained from...

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Literature Corpus work: 2eb464c5-b7f3-5202-990d-0fb03c84af1c
DOI: 10.21203/rs.3.rs-8825984/v1

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