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Article

Genome-wide methylation analysis shows similar patterns in Barrett’s esophagus and esophageal adenocarcinoma

29 Aug 2013

Abstract excerpt

Barrett's esophagus (BE) is a precursor of esophageal adenocarcinoma (EAC). To identify novel tumor suppressors involved in esophageal carcinogenesis and potential biomarkers for the malignant progression of BE, we performed a genome-wide methylation profiling of BE and EAC tissues. Using Illumina's Infinium HumanMethylation27 BeadChip microarray, we examined the methylation status of 27 578 CpG sites in 94...

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PMID: 23996928
DOI: 10.1093/carcin/bgt286

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