Article

Population Based Testing for Primary Prevention: A Systematic Review

2018-09-30

Abstract excerpt

The current clinical model for genetic-testing is based on clinical-criteria/family-history(FH) and a pre-defined mutation probability threshold.  It requires people to develop cancer before identifying unaffected individuals in the family to target prevention. This process is inefficient, resource intense and misses >50% of individuals/mutation carriers at risk. Population genetic-testing can overcome the...

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Literature Corpus work: 2e7e21c7-d89c-57f1-8ca2-69fd38f8f074
DOI: 10.20944/preprints201809.0602.v1

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