Article
Population Screening for Inherited Predisposition to Breast and Ovarian Cancer.
Annual review of genomics and human genetics - 31 Aug 2020
Manchanda Ranjit, Lieberman Sari, Gaba Faiza, Lahad Amnon, Levy-Lahad Ephrat
Abstract excerpt
The discovery of genes underlying inherited predisposition to breast and ovarian cancer has revolutionized the ability to identify women at high risk for these diseases before they become affected. Women who are carriers of deleterious variants in these genes can undertake surveillance and prevention measures that have been shown to reduce morbidity and mortality. However, under current strategies, the vast...
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