Article
Microsatellite analysis of malaria parasites.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Orjuela-Sánchez Pamela, Brandi Michelle C, Ferreira Marcelo U
Abstract excerpt
Microsatellites have been increasingly used to investigate the population structure of malaria parasites, to map genetic loci contributing to phenotypes such as drug resistance and virulence in laboratory crosses and genome-wide association studies and to distinguish between treatment failures and new infections in clinical trials. Here, we provide optimized protocols for genotyping highly polymorphic...
Topics
- Animals
- DNA Primers
- DNA, Protozoan
- Genome, Protozoan
- Genotype
- Humans
- Malaria, Falciparum
- Malaria, Vivax
- Microsatellite Repeats
- Plasmodium falciparum
- Plasmodium vivax
- Polymerase Chain Reaction
