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Supporting materials: Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of Port Wine Birthmark

2023-07-02

Abstract excerpt

<h4> Abstract </h4> <h4>Background</h4> Port wine birthmark (PWB) is a congenital vascular malformation resulting from developmentally defective endothelial cells (ECs). Developing clinically relevant disease models for PWB studies is currently an unmet need. <h4>Objective</h4> Our study aims to generate PWB-derived induced pluripotent stem cells (iPSCs) and iPSC-derived ECs that preserve disease-related pheno...

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Literature Corpus work: 2e5ec25c-cb22-5b67-933a-453e360a3088
DOI: 10.1101/2023.07.02.547408

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