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The unique tropism of <i>Mycobacterium leprae</i> to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A

2018-07-20

Abstract excerpt

Leprosy is a chronic infection where the skin and peripheral nervous system is invaded by Mycobacterium leprae . The infection mechanism remains unknown in part because culture methods have not been established yet for M.leprae. Mce1A protein (442 aa) is coded by mce1A (1326 bp) of M.leprae . The mce1A homolog in Mycobacterium tuberculosis is known to be associated with M.tuberculosis epithelial cell entry, a...

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Literature Corpus work
2e20c47d-111e-5453-9039-67c3b33bcf33
DOI
10.1101/373324
Open publication

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