Article
Comparative genomics of fatal ST308/O11 Pseudomonas aeruginosa from Egypt characterizes conserved resistance architecture, integron-associated multidrug resistance modules, and blaNDM-1 resistance islands.
BMC microbiology - 8 Aug 2026
Sanad Ahmed A, El-Sherbeny Ghada A, El-Morsi Adel A, Gad Ahmed F, Gebeer Hossam I, Seadawy Mohamed G
Abstract excerpt
Pseudomonas aeruginosa is a major cause of ventilator-associated pneumonia (VAP) and is increasingly associated with extensive antimicrobial resistance, limiting therapeutic options and contributing to poor clinical outcomes. The emergence of high-risk clones that combine multidrug resistance and virulence-associated traits represents a growing public health concern.In this study, 100 clinical P. aeruginosa...
Topics
- Pseudomonas aeruginosa
- Drug Resistance, Multiple, Bacterial
- Humans
- Integrons
- Anti-Bacterial Agents
- Pseudomonas Infections
- Egypt
- Genomic Islands
- Phylogeny
- Genome, Bacterial