Back to search

Article

Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular Morphogenesis

2025-04-19

Abstract excerpt

The eye is a complex organ composed of two main structures – the retina and the lens. It forms by the invagination of the lens forming head surface ectoderm embedding into the forming optic cup. This “outside-in” mode of morphogenesis ensures that the light focusing lens is positioned centrally inside of the eye in the highly constrained environment of the developing embryo. Advances in stem cell biology in the la...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2c6673ea-1ff7-538b-94c1-e59e9363a8f9
DOI
10.1101/2025.04.17.649366
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular MorphogenesisDOI 10.1101/2025.04.17.649366
Fish primary embryonic stem cells self-assemble into retinal tissue mirroring <i>in vivo</i> early eye developmentSemantic proximity
Building the developmental oculome: systems biology in vertebrate eye development and diseaseSemantic proximity
Eye lens organoids going simple: characterization of a new 3-dimensional organoid model for lens development and pathologySemantic proximity
Multiocular organoids from human induced pluripotent stem cells displayed retinal, corneal, and retinal pigment epithelium lineagesSemantic proximity
Setting Eyes on the Retinal Pigment EpitheliumSemantic proximity
Eye development.Semantic proximity
Multi-ocular Organoids from Human iPS Cells Displayed Retina, Cornea, and RPE LineagesSemantic proximity
Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cellsSemantic proximity
The Ocular Lens EpitheliumSemantic proximity
Co-ordinated ocular development from human iPS cells and recovery of corneal function.Semantic proximity
The Zebrafish as a Model Organism for Eye DevelopmentSemantic proximity
Teleost lens development and degeneration.Semantic proximity
Select a neighboring publication to make it the new centre.