Article

PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure

2024-03-04

Abstract excerpt

Sensory hair cells of the cochlea are essential for hearing, relying on the mechanosensitive stereocilia bundle at their apical pole for their function. Polycystic Kidney and Hepatic Disease 1-Like 1 (PKHD1L1) is a stereocilia protein required for normal hearing in mice, and for the formation of the transient stereocilia surface coat, expressed during early postnatal development. While the function of the stereoci...

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Literature Corpus work: 2baf4d26-8d48-530b-bd3c-f5a31897c0fb
DOI: 10.1101/2024.02.29.582786

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