Article
Combining Algorithms to Find Signatures That Predict Risk in Early-Stage Stomach Cancer.
Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2021
Nation J B, Cabot-Miller Justin, Segal Oren, Lucito Robert, Adaricheva Kira
Abstract excerpt
This study applied two mathematical algorithms, lattice up-stream targeting (LUST) and D -basis, to the identification of prognostic signatures from cancer gene expression data. The LUST algorithm looks for metagenes, which are sets of genes that are either overexpressed or underexpressed in the same patients. Whereas LUST runs unsupervised by clinical data, the D...
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