Incremental value in outcome prediction with gene expression–based signatures in diffuse large B-cell lymphoma

Abstract excerpt

Multiple gene expression-based signatures have been identified in diffuse large B-cell lymphoma that are predictive for survival outcomes. Most studies assess predictive significance based on P values from multivariable Cox regression. Few investigations have evaluated the incremental usefulness of these signatures. Recent developments in statistical methodology extend the use of concordance measures on censored...

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