Article

Subnetwork-based prognostic biomarkers exhibit performance and robustness superior to gene-based biomarkers in breast cancer

2018-03-28

Abstract excerpt

<h4>Background</h4> Effective classification of cancer patients into groups with differential survival remains an important and unsolved challenge. Biomarkers have been developed based on mRNA abundance data, but their replicability and clinical utility is modest. Integrating functional information, such as pathway data, has been suggested to improve biomarker performance. To date, however, the advantages of subn...

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Literature Corpus work: 3a2c6084-cc15-5fc2-85ba-66a5e0e4daa4
DOI: 10.1101/290924

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