Article

dTBI: A paradigm for closed-head injury in Drosophila

2020-06-18

Abstract excerpt

<title>Abstract</title> <p><italic>Drosophila</italic> models have been instrumental in providing insights into molecular mechanisms of neurodegeneration, that are applicable to human disease. We have recently described a model of controlled head injury to flies, which remarkably parallels many of the physiological responses of humans to traumatic brain injury (TBI). This protocol describes the construction, cali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: db99cbb5-def4-54ca-92ee-bf497ceb41bd
DOI: 10.21203/rs.3.pex-949/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

dTBI: A paradigm for closed-head injury in DrosophilaDOI 10.21203/rs.3.pex-949/v1Read

A Method to Inflict Closed Head Traumatic Brain Injury in DrosophilaSemantic proximity Read

Dynamic neural and glial responses of a head-specific model for traumatic brain injury in DrosophilaSemantic proximity Read

A <i>Drosophila</i> model of closed head traumatic brain injurySemantic proximity Read

Modeling Sex Differences and Neurodegeneration in Repetitive Traumatic Brain Injury Using <i>Drosophila</i>Semantic proximity Read

Mammalian Models of Traumatic Brain Injury and a Place for Drosophila in TBI ResearchSemantic proximity Read

Glial immune-related pathways as mediators of closed head TBI effects on behavior in <i>Drosophila</i>Semantic proximity Read

i Drosophila i models of traumatic brain injurySemantic proximity Read

Drosophila melanogaster as a model to study age and sex differences in brain injury and neurodegeneration after mild head traumaSemantic proximity Read

Glial immune-related pathways mediate effects of closed head traumatic brain injury on behavior and lethality in Drosophila.Semantic proximity Read

Genetic Modifiers Influencing the Acute and Long-Term Responses to Traumatic Brain Injury in <i>Drosophila</i>Semantic proximity Read

Age and Diet Affect Genetically Separable Secondary Injuries that Cause Acute Mortality Following Traumatic Brain Injury in Drosophila.Semantic proximity Read

A larval zebrafish model of TBI: Optimizing the dose of neurotrauma for discovery of treatments and aetiologySemantic proximity Read