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Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia

6 Nov 2008

Abstract excerpt

Cytogenetics has determined the incidence and prognostic significance of chromosomal abnormalities in acute lymphoblastic leukaemia (ALL). The development of fluorescence in situ hybridization (FISH) and array technologies has led to the discovery of novel aberrations. Five 'hot topics' are presented in which cytogenetics and related techniques have been instrumental in understanding the role of genetics in...

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PMID: 19006567
DOI: 10.1111/j.1365-2141.2008.07417.x

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