Article

Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy

2025-12-07

Abstract excerpt

Skeletal muscle is a structurally organized and functionally diverse organ composed of heterogeneous myofiber types and supporting non-myocyte populations that act in concert to generate force, regulate metabolism, and maintain systemic homeostasis. Myopathies occur in many different diseases, but the mechanisms that drive these muscle pathologies are still largely unknown, partly because conventional approaches c...

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Literature Corpus work: 2ac2ffcf-32ab-5619-a01a-bfe2f39b4072
DOI: 10.64898/2025.12.03.692123

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