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Integration of single-cell sequencing and experimental validation identified P2RY13/NF-κB as an immunological factor of patients with colorectal cancer

2026-08-10

Abstract excerpt

<title>Abstract</title> <p> Background Colorectal cancer (CRC) is a leading cause of mortality worldwide. Nevertheless, the functional heterogeneity of macrophages in the microenvironment of CRC and the corresponding mechanism during inflammation–cancer transition have not been fully elucidated. Methods Single-cell transcriptome sequencing (GSE144735), spatial transcriptome (10X Genomics), and The Cancer Genom...

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Literature Corpus work
2abe0937-5e28-5dae-bad3-aaa3d16439ab
DOI
10.21203/rs.3.rs-9796791/v1
Open publication

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Integration of single-cell sequencing and experimental validation identified P2RY13/NF-κB as an immunological factor of patients with colorectal cancerDOI 10.21203/rs.3.rs-9796791/v1
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