Article

Adipocyte p53 coordinates the response to cyclic fasting by regulating adipose tissue immune cell landscape

2023-07-12

Abstract excerpt

<title>Abstract</title> <p>In obesity, sustained adipose tissue (AT) inflammation constitutes a cellular memory that limits the effectiveness of weight loss interventions. Yet, the impact of fasting regimens on the regulation of AT immune infiltration is still elusive. Here, we show that cyclic intermittent fasting (IF) exacerbates the lipid-associated macrophage (LAM) inflammatory phenotype of visceral AT in obe...

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Literature Corpus work: 2a9fb649-abb0-5268-8cf1-3ca44651aa94
DOI: 10.21203/rs.3.rs-3082988/v1

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