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Article

Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma.

Nature communications - 14 Jun 2021

Raita Yoshihiko, Pérez-Losada Marcos, Freishtat Robert J, Harmon Brennan, Mansbach Jonathan M, Piedra Pedro A, Zhu Zhaozhong, Camargo Carlos A, Hasegawa Kohei

Abstract excerpt

Respiratory syncytial virus (RSV) bronchiolitis is not only the leading cause of hospitalization in U.S. infants, but also a major risk factor for asthma development. While emerging evidence suggests clinical heterogeneity within RSV bronchiolitis, little is known about its biologically-distinct endotypes. Here, we integrated clinical, virus, airway microbiome (species-level), transcriptome, and metabolome data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34127671
DOI: 10.1038/s41467-021-23859-6
PMCID: PMC8203688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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