Article

The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling

2023-03-15

Abstract excerpt

<title>Abstract</title> <p>The development of craniofacial skeletal structures is fascinatingly complex and elucidation of the underlying mechanisms will not only provide novel scientific insights, but also help develop more effective clinical approaches to the treatment and/or prevention of the numerous congenital craniofacial malformations. To this end, we performed CAGE-sequencing of the facial mesenchyme of h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a470c2d-4b27-55c6-843a-001e860791f8
DOI: 10.21203/rs.3.rs-2542333/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signalingDOI 10.21203/rs.3.rs-2542333/v1Read

mTORC2 Signaling Promotes Skeletal Growth and Bone Formation in MiceSemantic proximity Read

Fetal growth restriction exhibits various mTOR signaling in different regions of mouse placentas with altered lipid metabolismSemantic proximity Read

Zebrafish raptor mutation inhibits the activity of mTORC1, inducing craniofacial defects due to autophagy-induced neural crest cell death.Semantic proximity Read

Dissecting the Complexity of Skeletal-Malocclusion-Associated Phenotypes: Mouse for the Rescue.Semantic proximity Read

Spatially Organized IGF1-mTOR Signaling Controls Human Forebrain Progenitor Fate Through Coordinated Transcriptional and Translational ProgramsSemantic proximity Read

mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.Semantic proximity Read

mTOR driven gene transcription is required for cholesterol production in neurons of the developing cerebral cortexSemantic proximity Read

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.Semantic proximity Read

CSF1R-dependent macrophages control postnatal somatic growth and organ maturationSemantic proximity Read

Activation of Adipocyte mTORC1 Increases Milk Lipids in a Mouse Model of LactationSemantic proximity Read