Article
A bioactive phlebovirus-like envelope protein in a hookworm endogenous retrovirus
2021-11-24
Abstract excerpt
Endogenous retroviruses (ERVs), accounting for 14% of our genome, serve as a genetic reservoir from which new genes can emerge. Nematode ERVs are particularly diverse and informative of retrovirus evolution. We identify Atlas virus – a novel, intact ERV in the human hookworm Ancylostoma ceylanicum with an envelope protein genetically related to G N -G C glycoproteins from phleboviruses. A cryo-EM structure of A...
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Identifiers and source
- Literature Corpus work
- 29f3c48a-c966-5c68-93e7-26076fa05fe8
- DOI
- 10.1101/2021.11.23.469668
