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Article

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species.

Genome biology - 1 Jan 2010

Donati Claudio, Hiller N Luisa, Tettelin Hervé, Muzzi Alessandro, Croucher Nicholas J, Angiuoli Samuel V, Oggioni Marco, Dunning Hotopp Julie C, Hu Fen Z, Riley David R, Covacci Antonello, Mitchell Tim J, Bentley Stephen D, Kilian Morgens, Ehrlich Garth D, Rappuoli Rino, Moxon E Richard, Masignani Vega

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae is one of the most important causes of microbial diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed and compared with strains of non-pathogenic streptococci of the Mitis group. RESULTS: Despite evidence of extensive recombination, the S. pneumoniae phylogenetic tree revealed six major lineages. With the exception of serotype 1, the tree...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21034474
DOI: 10.1186/gb-2010-11-10-r107
PMCID: PMC3218663

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