Functional Domain Mutations in FAT4 Cadherin 21-34 Predicts Improved Prognosis in Gastric Cancer Patients: A Retrospective Study

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Gastric cancer is characterized by high incidence and mortality rates. Survival improvement relies on the identification of novel prognostic factors and the implementation of stratified precision therapy. FAT4, a crucial tumor suppressor gene, has been shown to be mutated in various tumor types. However, our understanding of the association between FAT4 mutation...

Topics

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• Cell Adhesion
• Chromatin
• CpG Islands
• Microsatellite Instability
• Receptor, IGF Type 1
• RNA, Untranslated
• Stomach Neoplasms
• Vascular Endothelial Growth Factor Receptor-2

Identifiers and source

Literature Corpus work

298bdfee-008e-5de4-98d9-6c89eb5b73c4

DOI

10.21203/rs.3.rs-4305060/v1