Article

StrataChip: a microphysiological system capturing dynamic keratinocyte fate and mechanical transitions during human epidermal morphogenesis

2026-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Epidermal development and homeostasis require precise coordination between keratinocyte differentiation and mechanics. Still, the mechanisms integrating these processes remain poorly understood in part due to limitations of existing experimental systems. Here, we introduce StrataChip, a tractable microphysiological system that enables dynamic, multimodal interrogation of human epidermal morphoge...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 29500e6b-6564-51c5-83db-3200756fc580
DOI: 10.64898/2026.03.26.714483

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

StrataChip: a microphysiological system capturing dynamic keratinocyte fate and mechanical transitions during human epidermal morphogenesisDOI 10.64898/2026.03.26.714483Read

Rete Ridge Topography as a Determinant of Epidermal Stem Cell Identity: Implications for Skin AgingSemantic proximity Read

Single cell transcriptomics of human epidermis identifies basal stem cell transition statesSemantic proximity Read

Single cell transcriptomics of human epidermis reveals basal stem cell transition statesSemantic proximity Read

Rete Ridge Topography as a Determinant of Epidermal Stem Cell Identity: Implications for Skin AgingSemantic proximity Read

A Targeted Spatial Transcriptomics Framework for a High-Resolution Human Skin Cell AtlasSemantic proximity Read

Spatiotemporal Single-Cell Roadmap of Human Skin Wound HealingSemantic proximity Read

Mammalian skin cell biology: At the interface between laboratory and clinicSemantic proximity Read

Development of an Integrated Single-Cell and Spatial Transcriptomics Atlas of Healthy Human Skin Focusing on the Pilosebaceous UnitSemantic proximity Read

Single-cell transcriptomics in dermatologySemantic proximity Read

Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell statesSemantic proximity Read

Spatiotemporal single-cell roadmap of human skin wound healingSemantic proximity Read

An Optimized Tissue Dissociation Protocol for Single-Cell RNA Sequencing Analysis of Fresh and Cultured Human Skin BiopsiesSemantic proximity Read