Article

Distinct Frailty Phenotypes Are Associated with Cognitive Performance and Brain Structure in Alzheimer’s Disease

2025-07-30

Abstract excerpt

<h4>Background: </h4> /Objectives: Frailty is a well-established risk factor for cognitive decline and dementia, yet how its distinct physical, functional, and psychosocial components relate to brain health in Alzheimer’s disease (AD) remains poorly understood. This proof-of-concept study aimed to identify data-driven frailty factors and examine their cross-sectional associations with cognition and brain structure...

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Literature Corpus work: 294fee81-2b0e-553d-b4a1-84e6729a939b
DOI: 10.20944/preprints202507.2235.v1

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