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A Highly Protective Clade 1 and 2 Cross-Reactive Pandemic Influenza Virus Vaccine Based on a 4th Generation Fully Deleted Adenoviral Vector of a Rare Serotype

2025-05-06

Abstract excerpt

<h4>ABSTRACT</h4> The GreVac vaccine technology was created as a fast and flexible plug-and-play vaccine platform based on a 4th generation architecture of fully deleted (fd) helper virus-independent (hi) adenoviral (Ad) vectors. For the initial proof-of-principle studies, we at Greffex had engineered an avian influenza vaccine, which delivered a transgene expression cassette for an avian influenza virus H5 hemag...

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Literature Corpus work
28d478a1-8a33-5fb9-9140-a54cfe98bd3f
DOI
10.1101/2025.04.30.651579
Open publication

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