Article

Evaluation of diversity levels of the integrase gene sequences coming from HIV-1 virus, supporting the lack of target specificity of ivermectin <i>versus</i> the integrase-importin complex in SARS-CoV-2 infection

2020-07-20

Abstract excerpt

Therapies with new drugs have been appearing in tests worldwide as potential inhibitors of sars-cov-2 virus replication. Recently, one of these drugs, Ivermectin, was reported as an inhibitor of the nuclear import of HIV-1 proteins in vitro , soon becoming the target of an international prospecting work (not yet published), with patients tested for COVID-19. However, understanding the evolutionary aspects of the...

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Literature Corpus work: 2875b2cd-b60f-528f-bc89-9657f3a9b362
DOI: 10.1101/2020.07.18.210096

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