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Enhancing evidence-based guidelines using trial emulation in electronic health records: Real-world effects of empagliflozin in people with type 2 diabetes

2025-09-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> There is growing interest in widening the use of sodium-glucose co-transporter-2 inhibitors (SGLT2i) to all people with type 2 diabetes mellitus (T2DM). However, pivotal randomised controlled trials (RCTs) evaluated these drugs only in highly selected populations, often lacking generalisability to real-world populations. Understanding the effects of SGLT2i in populations, wh...

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Literature Corpus work
27f1eefe-e33d-58f6-ae59-cb8cfa76eef9
DOI
10.1101/2025.09.17.25335885
Open publication

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Enhancing evidence-based guidelines using trial emulation in electronic health records: Real-world effects of empagliflozin in people with type 2 diabetesDOI 10.1101/2025.09.17.25335885
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