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Therapy to Teratology: Chronic Paternal Antioxidant Supplementation Alters Offspring Placental Architecture and Craniofacial Morphogenesis in a Mouse Model

2025-09-10

Abstract excerpt

Oxidative stress plays a significant role in regulating the mammalian epigenome, with emerging evidence suggesting imbalances in the cellular redox state trigger stress-responsive epigenetic modifications that drive various human diseases. However, it remains unclear whether, like worms, epigenetic changes caused by redox imbalance or mitochondrial stress can move through the mammalian germline, potentially affect...

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Identifiers and source

Literature Corpus work
27e7a141-d3ef-582c-85fa-fca2162f730c
DOI
10.1101/2025.09.05.674556
Open publication

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Therapy to Teratology: Chronic Paternal Antioxidant Supplementation Alters Offspring Placental Architecture and Craniofacial Morphogenesis in a Mouse ModelDOI 10.1101/2025.09.05.674556
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