Back to search

Article

A Novel Multiplex qPCR Assay for Detection of <i>Plasmodium falciparum</i> with <i>Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3)</i> Deletions in Polyclonal Infections

2020-02-02

Abstract excerpt

<h4>Background</h4> Rapid diagnostic tests (RDTs) that detect the malaria antigen histidine-rich protein 2 (HRP2) are widely used in endemic areas globally to confirm Plasmodium falciparum infection in febrile patients. The emergence of parasites lacking the gene encoding HRP2 and escaping RDT detection threatens progress in malaria control and elimination. Many health facilities in malaria endemic countries are...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
27e5e753-6bde-5fd6-90dd-aeb5c5590452
DOI
10.1101/2020.01.31.928986
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A Novel Multiplex qPCR Assay for Detection of <i>Plasmodium falciparum</i> with <i>Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3)</i> Deletions in Polyclonal InfectionsDOI 10.1101/2020.01.31.928986
A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infectionsSemantic proximity
Malaria Rapid Diagnostic Tests: very low prevalence of Plasmodium falciparum histidine-rich protein 2 (pfhrp2) deletion in the Brazil-Venezuela-Guyana tri-borderSemantic proximity
Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparumSemantic proximity
<i>Plasmodium falciparum w</i>ith<i>pfhrp2/3</i>deletion not detected in a 2018-2021 malaria longitudinal cohort study in Kinshasa Province, Democratic Republic of the CongoSemantic proximity
Causes of false-negative rapid diagnostic tests for symptomatic malaria in the DRCSemantic proximity
Prevalence of Plasmodium falciparum Isolates Lacking the Histidine Rich Protein 2 Gene Among Symptomatic Malaria Patients in Kwilu Province, DR. Congo.Semantic proximity
Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland TanzaniaSemantic proximity
<i>Plasmodium falciparum pfhrp2</i> and <i>pfhrp3</i> Gene Deletions from Persons with Symptomatic Malaria Infection in Ethiopia, Kenya, Madagascar, and RwandaSemantic proximity
Extensive Deletion and Sequence Variation of Plasmodium Falciparum Histidine Rich Protein 2/3 (pfhrp2/3) Genes in Ethiopia: Implication for RDT-based Malaria Diagnosis and ControlSemantic proximity
Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland TanzaniaSemantic proximity
Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions and Their Implications in Malaria ControlSemantic proximity
Evaluating Malaria Rapid Diagnostic Tests and Microscopy for Detecting Plasmodium Infection and Status of Plasmodium falciparum Histidine-Rich Protein 2/3 Gene Deletions in Southeastern NigeriaSemantic proximity
Select a neighboring publication to make it the new centre.